Status:

TERMINATED

Study of Brimonidine and Timolol Ophthalmic Solution With Latanoprost Compared With Latanoprost in Glaucoma Patients

Lead Sponsor:

Allergan

Conditions:

Glaucoma, Angle-Closure

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

This study will evaluate the safety and efficacy of patients switched from latanoprost monotherapy to a combination therapy of latanoprost with COMBIGAN® (brimonidine 0.2%/timolol 0.5% fixed combinati...

Eligibility Criteria

Inclusion

  • Patient has been administering latanoprost eye drops in affected eye(s) for at least 12 weeks prior to study
  • Patient must have at least partially responded to latanoprost and requiring further IOP lowering eye drops
  • Diagnosis of chronic angle-closure glaucoma
  • Patients using COMBIGAN® in the past must not have been discontinued due to adverse events or lack of efficacy.

Exclusion

  • Known allergy or hypersensitivity to COMBIGAN®
  • Corneal abnormalities that would preclude accurate IOP readings
  • Any other active ocular disease other than glaucoma or ocular hypertension
  • Ocular surgery within the past 3 months.

Key Trial Info

Start Date :

November 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 1 2012

Estimated Enrollment :

17 Patients enrolled

Trial Details

Trial ID

NCT01151904

Start Date

November 1 2009

End Date

February 1 2012

Last Update

February 6 2013

Active Locations (1)

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1

Bangkok, Thailand

Study of Brimonidine and Timolol Ophthalmic Solution With Latanoprost Compared With Latanoprost in Glaucoma Patients | DecenTrialz