Status:
COMPLETED
Platelet Reactivity In Patients With Nuisance Bleeding On A Thienopyridine
Lead Sponsor:
Medstar Health Research Institute
Conditions:
Platelet Aggregation
Bleeding
Eligibility:
All Genders
18+ years
Brief Summary
The objective is to describe and quantify levels of platelet reactivity in three different cohorts of patients taking thienopyridine: patients who report nuisance bleeding, patients who report alarmin...
Eligibility Criteria
Inclusion
- Patients 18 years or older from both genders
- Underwent PCI within the last year
- Taking maintenance dose of clopidogrel 75 mg once a day or prasugrel 10 mg once a day for at least five days
Exclusion
- Known allergies to aspirin, clopidogrel, or prasugrel.
- Use of a glycoprotein (GP)IIb/IIIa inhibitor within 8 hours of the blood draw.
- Patient known to be pregnant or lactating
- Patient with known history of anemia, thrombocytopenia, bleeding disorder, or currently active bleeding
- On warfarin therapy at the time of blood draw
- Known blood transfusion within the preceding 10 days of the blood draw
- Patients treated with non-steroidal anti-inflammatory drugs (NSAIDS, not to include aspirin) within the previous 5 days
- Any significant medical condition that, in the investigator's opinion, may interfere with the patient's optimal participation in the study.
Key Trial Info
Start Date :
April 1 2010
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
July 1 2011
Estimated Enrollment :
300 Patients enrolled
Trial Details
Trial ID
NCT01152229
Start Date
April 1 2010
End Date
July 1 2011
Last Update
August 3 2011
Active Locations (1)
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1
Washington Hospital Center
Washington D.C., District of Columbia, United States, 20010