Status:
COMPLETED
Intubating Condition After Magnesium Pre-treatment
Lead Sponsor:
Seoul National University Bundang Hospital
Conditions:
Easy of Laryngoscopy Manipulation
Vocal Cord Position or Movement
Eligibility:
All Genders
20-65 years
Phase:
NA
Brief Summary
Magnesium had an inhibitory effect on neuromuscular transmission and caused a decrease in muscle fiber membrane excitability. It reduces the amount of acetylcholine that is released at the motor nerve...
Eligibility Criteria
Inclusion
- patients undergoing operation under general anesthesia
- American Society of Anesthesiologist physical status I or II
- 20-65 year old male or female
Exclusion
- hepatic or renal dysfunction
- respiratory or cardiovascular dysfunction
- neurologic disorder
- neuromuscular disease
- pregnancy
- body mass index (BMI) \>30 kg/m2 or \<16.5 kg/m2
- anticipated difficult airway
- higher magnesium level than normal range in preoperative evaluation
- chronic medication with calcium channel blocker or magnesium
- history of known allergy to magnesium sulphate or any other study drugs
Key Trial Info
Start Date :
December 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2011
Estimated Enrollment :
168 Patients enrolled
Trial Details
Trial ID
NCT01153256
Start Date
December 1 2010
End Date
March 1 2011
Last Update
January 9 2012
Active Locations (1)
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1
Seoul National University Bundang Hospital
Seongnam-si, Gyeonggi-do, South Korea, 463-707