Status:
COMPLETED
Diabetes and Gastric By- Pass
Lead Sponsor:
University of Texas Southwestern Medical Center
Conditions:
Type 2 Diabetes
Eligibility:
All Genders
18-65 years
Brief Summary
The purpose of this study is to evaluate the mechanisms leading to rapid postoperative improvement in diabetes following Gastric By-Pass surgery for obesity.We will evaluate and compare the changes in...
Detailed Description
Volunteers planned to undergo RYGB will be studied during two-9 days periods of identical and controlled diet and activity, separated by a 4-10-week washout period. Study Period #1: This first study...
Eligibility Criteria
Inclusion
- volunteers that are planned to undergo RYGB(Roux-en-Y By pass) and have type 2 diabetes diagnosed within the prior 10 years.
Exclusion
- abnormal renal function
- significant anemia
- difficult venous access
- treatment with incretin mimetics or DPP IV inhibitors in the prior 3 months
- recent change in use of any pharmacologic agent with potential effect on either beta-cell function or insulin resistance.
- pregnancy
- non -English speakers
Key Trial Info
Start Date :
June 1 2010
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 1 2012
Estimated Enrollment :
22 Patients enrolled
Trial Details
Trial ID
NCT01153516
Start Date
June 1 2010
End Date
December 1 2012
Last Update
March 27 2019
Active Locations (1)
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1
Clinical and Translational Research Center
Dallas, Texas, United States, 75390