Status:

COMPLETED

Schema Focused Therapy for Chronic Depression

Lead Sponsor:

Maastricht University Medical Center

Collaborating Sponsors:

Academic Community Mental Health Centre (RIAGG)

Conditions:

Chronic Major Depressive Disorder

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

Schema focused therapy (SFT) is an innovative treatment approach to chronic, lifelong problems that incorporates cognitive, behavioral, experiential and psychodynamic elements and techniques. This stu...

Detailed Description

A single-case series design with multiple randomized baselines across participants will be used in this study. The study will last approximately 36 months and comprises three phases. The first phase i...

Eligibility Criteria

Inclusion

  • Chronic MDD as defined by the DSM-IV (meeting full criteria of MDD for at least 2 years).
  • Beck Depression Inventory II (BDI-II) score at screening \>=20 (moderate to severe depression)
  • Can understand and speak the Dutch language
  • Has internet access at home

Exclusion

  • Acute suicide risk
  • Substance induced mood disorder
  • Medical condition causes depression directly or through medication intake
  • MDD with psychotic features
  • DSM-IV Bipolar disorder (current or past)
  • DSM-IV Psychotic disorder (current or past)
  • DSM-IV alcohol or drug dependence
  • Autism Spectrum Disorders (Autistic Disorder, Asperger Syndrome, Pervasive developmental disorder NOS, Rett syndrome, Childhood disintegrative disorder)
  • Cluster A and Cluster B personality disorders
  • Started with antidepressant medication within three months prior to initial screening. Patients who receive antidepressant medication for more than 3 months prior to the start of the study can keep taking their medication and will not be excluded from participation.
  • MRI contra-indications, such as claustrophobia, metal parts in the body and, for women, current pregnancy or breastfeeding.

Key Trial Info

Start Date :

January 1 2011

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 1 2016

Estimated Enrollment :

25 Patients enrolled

Trial Details

Trial ID

NCT01153867

Start Date

January 1 2011

End Date

January 1 2016

Last Update

March 16 2016

Active Locations (1)

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Academic Community Mental Health Center, Riagg

Maastricht, Limburg, Netherlands, 6221BD