Status:
COMPLETED
Inflammatory and Immune Profiling of Kidney Tissue Obtained From Patients With Newly Diagnosed Kidney Disease
Lead Sponsor:
The Rogosin Institute
Collaborating Sponsors:
Janssen Research & Development, LLC
Conditions:
Proteinuria
Kidney Injury
Eligibility:
All Genders
18-90 years
Brief Summary
This study will evaluate in patients with kidney disease, the role that certain inflammatory and immune mediators play in promoting kidney damage. The investigators hypothesize that certain mediators,...
Detailed Description
The aim of the study is to evaluate in humans inflammatory and immune mediators that may play a role in kidney damage. The investigators hypothesize that certain inflammatory and immune mediators iden...
Eligibility Criteria
Inclusion
- Male and females, 18 years to 90 years old
- Any subject with pre-existing clinical indication of a kidney biopsy including, but not limited to, nephritic syndrome, nephritic syndrome or proteinuric disease state. Additionally, kidney transplant donors will be included for purpose of obtaining control tissue.
- Willing and able to give consent
- Additionally, kidney transplant donors and patients requiring nephrectomy for removal of renal mass will be included for purpose of obtaining control tissue.
Exclusion
- Subjects on longstanding immunosuppressive agents (empiric initiation of glucocorticoid therapy within 48 hours prior to kidney biopsy is acceptable)
- Kidney transplant recipient
- Inability to follow-up for future protocol laboratory evaluation
Key Trial Info
Start Date :
July 1 2010
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
November 1 2016
Estimated Enrollment :
119 Patients enrolled
Trial Details
Trial ID
NCT01156428
Start Date
July 1 2010
End Date
November 1 2016
Last Update
March 15 2024
Active Locations (1)
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1
The Rogosin Institute
New York, New York, United States, 10021