Status:

COMPLETED

Catalytic Antibodies and Lupus in Martinique

Lead Sponsor:

University Hospital Center of Martinique

Conditions:

Systemic Lupus Erythematosus

Eligibility:

All Genders

18+ years

Brief Summary

* The Martinique island (French West-Indies) is an area of high prevalence and incidence for Systemic Lupus Erythematosus (SLE), respectively 64,2/ 100000 and 4,7/ 100000. In many cases, this disease ...

Detailed Description

This study will be conducted as an case-control survey. * The first group with patients: 60 SLE patients, 30 patients with a quiescent lupus and 30 patients with an active lupus. Patients that will b...

Eligibility Criteria

Inclusion

  • For patients:
  • Presence of systemic lupus erythematosus according to the criteria of the modified 1997 ARA 1982 Lupus systemic evolution: Rates of anti DNA\> 100 U/L in ELISA and SLEDAI\> 7. Quiescent systemic Lupus: SLEDAI \<7
  • Be aged 18 years and over
  • Patient who has his main home in Martinique
  • Patient who gave his agreement to participate in this clinical study
  • For control subjects:
  • Voluntary donor who gave freely his agreement to participate in this study
  • Be aged 18 years and over
  • Patient who has his main home in Martinique
  • Voluntary who gave his agreement to participate in this clinical study

Exclusion

  • For patients:
  • Presence of mixed connective tissue disease, Hashimoto
  • Patients with other diseases: cancer, current infection
  • Patient pregnant or breast-feeding
  • Patient who refuse to participate in the study
  • Patient not affiliated with a social security scheme (beneficiary or beneficiary)
  • Specially Protected Persons (or under guardianship)
  • Patient who has not his main home in Martinique
  • For control subjects:
  • Voluntary donor who refused to participate in this study
  • Voluntary who has not main home in Martinique

Key Trial Info

Start Date :

January 1 2012

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 1 2013

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT01157468

Start Date

January 1 2012

End Date

December 1 2013

Last Update

September 8 2016

Active Locations (1)

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1

Centre Hospitalier Universitaire de Fort de France

Fort de France, Martinique, France, 97261