Status:
COMPLETED
Effect of Preoperative Pregabalin on Propofol Induction Dose
Lead Sponsor:
Université de Sherbrooke
Conditions:
Anesthesia, General
Laparoscopic Surgery
Eligibility:
FEMALE
18-40 years
Phase:
PHASE4
Brief Summary
The primary issue is to determine whether preoperatively administered pregabalin decreases the necessary dose of propofol during induction of general anesthesia. The investigators secondary issue is t...
Eligibility Criteria
Inclusion
- Laparoscopic gynaecologic surgery
- Age 18-40 years
- ASA class I or II
- Body mass index 18-30
Exclusion
- Allergic to pregabalin or gabapentin
- Chronic renal failure
- Alcohol or drug abuse
- Chronic analgesic use other than acetaminophen or NSAID
- Already taking gabapentin, pregabalin, benzodiazepin or antidepression drug
- Known neurological deficiency
- Suspected difficult intubation or ventilation
- Atypical pseudocholinesterases
Key Trial Info
Start Date :
April 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 1 2011
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT01158859
Start Date
April 1 2010
End Date
August 1 2011
Last Update
November 7 2012
Active Locations (1)
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1
Centre Hospitalier Universitaire de Sherbrooke
Sherbrooke, Quebec, Canada, J1H 5N4