Status:
COMPLETED
A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of MEMP1972A in Patients With Allergic Rhinitis
Lead Sponsor:
Genentech, Inc.
Conditions:
Allergic Rhinitis
Eligibility:
All Genders
18-55 years
Phase:
PHASE1
Brief Summary
This is a Phase Ib, randomized, blinded, placebo-controlled, multiple-ascending dose study in patients with seasonal or perennial allergic rhinitis to investigate the safety, tolerability, and pharmac...
Eligibility Criteria
Inclusion
- Diagnosis of allergic rhinitis
- In good health, determined by no clinically significant findings from medical history, 12-lead ECG, and vital signs
- Males or females who are surgically sterilized, post menopausal for the past year, or are using two acceptable methods of contraception against pregnancy through at least 6 months after the dose of study drug
Exclusion
- History or clinical manifestations of significant metabolic, hepatic, renal, hematologic, immunodeficiency, pulmonary, cardiovascular, gastrointestinal, urologic, neurologic, or psychiatric disorders
- History of anaphylaxis, hypersensitivity or drug allergies
- Use of a non-biologic investigational drug or participation in an investigational study with a non-biologic drug within 30 days prior to dosing
- Use of a biologic investigational therapy or participation in an investigational study involving biologic therapy within 3 months prior to dosing
- Positive blood test for chronic viral infections by: hepatitis B surface antigen, hepatitis C virus antibody, or HIV antibody
Key Trial Info
Start Date :
July 11 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2011
Estimated Enrollment :
36 Patients enrolled
Trial Details
Trial ID
NCT01160861
Start Date
July 11 2010
End Date
April 1 2011
Last Update
December 12 2022
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