Status:
TERMINATED
Detailed Clinical, Biochemical and Genetic Characterization in Gonadotropin-releasing Hormone (GnRH) Deficiency Disorders
Lead Sponsor:
Massachusetts General Hospital
Conditions:
Idiopathic Hypogonadotropic Hypogonadism
Hypothalamic Amenorrhea
Eligibility:
All Genders
18-40 years
Brief Summary
In this study, we will measure levels of reproductive hormones and metabolic markers in subjects with isolated GnRH deficiency disorders and compare them to healthy control populations. Our goals are ...
Eligibility Criteria
Inclusion
- Over the age of 18 for men
- Between the ages of 18 and 40 for women
- For reproductive disorder population: Current or previous diagnosis of Idiopathic Hypogonadotropic Hypogonadism or Hypothalamic Amenorrhea
Exclusion
- chronic disease (hypertension, high cholesterol, diabetes, asthma, etc)
- polycystic ovarian syndrome for women
- prescription medication use (other than allergy meds) for control populations
- irregular menstrual cycles for healthy female control population (cycle length longer than 35 days or shorter than 25 days. cycle length varies by more than 5 days. less than 9 periods per year)
Key Trial Info
Start Date :
June 1 2010
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
October 1 2010
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT01165619
Start Date
June 1 2010
End Date
October 1 2010
Last Update
May 24 2011
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Massachusetts General Hospital
Boston, Massachusetts, United States, 02114