Status:
UNKNOWN
Exercise Study Including Patients With Hypertrophic Cardiomyopathy
Lead Sponsor:
Stanford University
Collaborating Sponsors:
University of Michigan
Conditions:
Cardiomyopathy, Hypertrophic
Eligibility:
All Genders
18-80 years
Brief Summary
The long term health and cardiovascular benefits of a regular exercise program have been well-established. National guidelines recommend involvement in moderate aerobic fitness (i.e. walking, bicyclin...
Eligibility Criteria
Inclusion
- Ages 18 - 80 years old.
- Diagnosis of hypertrophic cardiomyopathy, defined by the presence of unexplained left-ventricular hypertrophy (wall thickening) \> 13 mm in any wall segment.
- Exercise £ 30 minutes, 1 day per week for the previous 3 months.
- Agreement to be a participant in the study protocol and willing/able to return for follow-up.
Exclusion
- History of exercise-induced syncope or arrhythmias (ventricular tachycardia or non-sustained ventricular tachycardia).
- Medically refractory LV outflow tract obstruction being evaluated for septal reduction therapy.
- Less than 3 months post septal reduction therapy (surgery or catheter based intervention).
- Hypotensive response to exercise (\> 20 mmHg drop in systolic blood pressure from peak blood pressure to post exercise blood pressure).
- Pregnancy.
- ICD placement in last 3 months or scheduled.
- Life expectancy less than 12 months.
- Inability to exercise due to orthopedic or other non-cardiovascular limitations.
Key Trial Info
Start Date :
May 1 2010
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
April 1 2012
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT01165749
Start Date
May 1 2010
End Date
April 1 2012
Last Update
July 20 2010
Active Locations (1)
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1
Stanford University School of Medicine
Stanford, California, United States, 94305