Status:
COMPLETED
Longitudinal Study of Patients Following Long Bone Fracture
Lead Sponsor:
Barts & The London NHS Trust
Collaborating Sponsors:
London Deanery
Conditions:
Vitamin D
Long Bone Fracture
Eligibility:
All Genders
16+ years
Brief Summary
Studies in chickens show that blood levels of a particular form of vitamin D (called 24,25-dihydroxvitamin D) increase after bone fracture. Laboratory studies show that this form of vitamin D helps th...
Eligibility Criteria
Inclusion
- Any cross-shaft long bone or clavicle fracture within last 12 hours
- Able to give written informed consent
- Age ≥ 16 years
- Fused physes (physiologically adult)
Exclusion
- Taking medication affecting vitamin D metabolism - carbamazepine, phenobarbital, phenytoin or primidone
- Taking vitamin D supplement \> 800 IU/day
- Abdominal visceral injury, pleural injury (except pneumothorax), spinal cord injury, or GCS \< 15 at presentation to hospital
- Known Paget's disease, osteopetrosis, metastatic bone cancer, or primary bone cancer
- Current prisoners
- Currently taking part in another clinical research project
Key Trial Info
Start Date :
March 1 2010
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
October 1 2010
Estimated Enrollment :
33 Patients enrolled
Trial Details
Trial ID
NCT01170572
Start Date
March 1 2010
End Date
October 1 2010
Last Update
November 7 2012
Active Locations (1)
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1
The Royal London Hospital
London, London, United Kingdom, E1 1BB