Status:

TERMINATED

Clinical Status Monitoring in Implantable Cardiac Defibrillator (ICD) Patients by Physiological Diagnosis (PhD) Function

Lead Sponsor:

LivaNova

Conditions:

Heart Failure

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

The purpose of this study is to evaluate the performance of advanced features, that have been implemented in the PARADYM ICD Platform offering single chamber (VR - model 8250), dual Chamber (DR - 8550...

Detailed Description

The study will particularly focus on a new sensor-based diagnostic feature, called PhD-Clinical Status (PhD). A dedicated PhD screen shows the trends of patients' ventilation levels at rest (MVR) and ...

Eligibility Criteria

Inclusion

  • Patient eligible for implantation of an ICD or a CRT-D device according to current available guidelines.
  • Documented chronic HF (NYHA Class II to IV) at the time of enrollment
  • Scheduled for implant of a PARADYM ICD / CRT-D or implanted within the previous month
  • Signed and dated informed consent

Exclusion

  • Any contraindication for ICD therapy
  • Abdominal implantation site
  • Acute myocarditis
  • Unstable coronary symptoms (unstable angina or myocardial infarction) within the last month
  • Planned heart transplant
  • Mechanical tricuspid valve
  • Unable to perform the 6 minute Walking Test at time of enrollment
  • Already included in another clinical study
  • Life expectancy less than 13 months
  • Inability to understand the purpose of the study or refusal to cooperate
  • Inability or refusal to provide informed consent
  • Under guardianship
  • Age of less than 18 years
  • Pregnancy (Women of childbearing potential should have a negative pregnancy test prior to enrollment)

Key Trial Info

Start Date :

September 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 1 2011

Estimated Enrollment :

388 Patients enrolled

Trial Details

Trial ID

NCT01170624

Start Date

September 1 2009

End Date

September 1 2011

Last Update

January 12 2015

Active Locations (25)

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Page 1 of 7 (25 locations)

1

Algemeen Ziekenhuis Middelheim Lindendref 1 2020 Antwerpen

Antwerp, Belgium, 2020

2

Centre Hospitalier Général

Albi, France, 81013

3

Centre Hospitalier Universitaire D'Amiens

Amiens, France, 80090

4

Chu Annecy

Annecy, France, 74011