Status:
COMPLETED
Effect of Neutrophil Elastase Inhibitor on Lung Injury After Esophagectomy
Lead Sponsor:
Yokohama City University Medical Center
Conditions:
Esophageal Cancer
Eligibility:
All Genders
55-77 years
Phase:
NA
Brief Summary
A neutrophil elastase inhibitor may have effect on suppression of the lung injury after thoransthoracic esophagectomy. The investigators hypothesized that postoperative complication, particularly resp...
Detailed Description
The aim of this study was to clarify the usefulness of perioperative administration of sivelestat sodium hydrate, a selective inhibitor of neutrophil elastase in the pulmonary function, systemic infla...
Eligibility Criteria
Inclusion
- Thoracic esophageal squamous cell carcinoma
Exclusion
- Preoperative chemoradiotherapy
- Cardiovascular disease with NYHA grade III or IV
- Pulmonary disorder with Hugh-Jones classification II, III, IV, or V, preo
- Liver cirrhosis
- Renal failure
Key Trial Info
Start Date :
March 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2009
Estimated Enrollment :
31 Patients enrolled
Trial Details
Trial ID
NCT01170845
Start Date
March 1 2007
End Date
March 1 2009
Last Update
July 27 2010
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Chikara Kunisaki
Yokohama, Kanagawa, Japan, 232-0024