Status:
COMPLETED
Soy Nut Study on Markers of Health
Lead Sponsor:
University of California, Davis
Conditions:
Metabolic Syndrome X
Eligibility:
All Genders
21+ years
Phase:
NA
Brief Summary
The investigators hope to learn about the effects of soy nuts on markers of health. When some people eat soy foods, their gut bacteria make equol. Equol is a soy metabolite (small molecule made during...
Detailed Description
The objective of the study is to investigate the metabolomic response to consumption of soy protein containing polyphenolic phytochemicals (isoflavones). The aim of this pilot study is to demonstrate ...
Eligibility Criteria
Inclusion
- Postmenopausal women
- Men ages 45 or above
- Blood pressure greater than or equal to 130/85 mmHg but not greater than 160/100 and meeting an additional 2 of the remaining 4 Metabolic syndrome diagnostic criteria as defined by NCEP ATP III:
- Elevated waist circumference: men equal to or greater than 40 inches, women equal to or greater than 35 inches
- Reduced HDL cholesterol: men less than 40 mg/dL, women less than 50 mg/dL
- Fasting glucose greater than or equal to 100 mg/dL
- Fasting blood triglycerides greater than or equal to 150 mg/dL but less than 400 mg/dL
- Weight of at least 110 pounds
Exclusion
- Smokers
- Chronic disease, such as diabetes, cancer, renal disease, and blood disorders
- History of intestinal disorders, which affect absorption or transit, such as ulcerative colitis or crohns disease
- Allergy to soy
- Antioxidant supplement usage
Key Trial Info
Start Date :
August 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2012
Estimated Enrollment :
18 Patients enrolled
Trial Details
Trial ID
NCT01173380
Start Date
August 1 2010
End Date
September 1 2012
Last Update
May 30 2017
Active Locations (1)
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1
Ragle Human Nutrition Center
Davis, California, United States, 95616