Status:
COMPLETED
Exploring the Role of Adipocyte Fatty Acid Binding Protein in the Association of Obstructive Sleep Apnea and Metabolic Dysfunction
Lead Sponsor:
The University of Hong Kong
Conditions:
Obstructive Sleep Apnea
Insulin Resistance
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
Adipocyte fatty acid binding protein (A-FABP) is a member of the FABP super family, is abundant in adipocytes and macrophages. Regulatory functions of A-FABP in lipid and glucose metabolism have been ...
Detailed Description
We hypothesize that there are changes in circulating A-FABP level which can be mitigated by effective treatment of OSA. The aim is to investigate the effect of CPAP treatment of OSA on circulating A-...
Eligibility Criteria
Inclusion
- Subjects between 18 - 65 years old
- Able to understand and give informed written consent
Exclusion
- BMI \> 35 kg/m2, and features of obesity hypoventilation syndrome
- known diabetes mellitus or hyperlipidemia on treatment
- known cardiovascular disease except hypertension stable on treatment
- unstable medical illness
- need for starting treatment for OSA or other medical conditions immediately
Key Trial Info
Start Date :
June 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2018
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT01173432
Start Date
June 1 2008
End Date
December 1 2018
Last Update
April 17 2019
Active Locations (1)
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1
The University of Hong Kong
Hong Kong, Hong Kong, 852