Status:
COMPLETED
Processed Residual Pump Blood in Cardiac Surgery: The PRBC Trial
Lead Sponsor:
Hamilton Health Sciences Corporation
Conditions:
Cardiopulmonary Bypass
Hemorrhage
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The study is an randomized controlled trial (RCT) of 198 coronary artery bypass graft (CABG) patients, exploring whether ultrafiltration of residual blood in the cardiopulmonary bypass circuit reduces...
Detailed Description
Blood products are a limited resource and cardiac surgery is a high consumer. Processing residual cardiopulmonary bypass (CPB) volume via ultrafiltration may improve hemostasis and reduce transfusion ...
Eligibility Criteria
Inclusion
- at least 18 years of age
- were to undergo isolated on-pump CABG
- were able to give informed consent
Exclusion
- performed autologous blood donation
- underwent off-pump CABG
- emergency procedure
- resternotomy
- known bleeding disorder not drug related
- history of heparin-induced thrombocytopenia
- Jehovah's Witness
- intra-operative catastrophe prior to randomization
Key Trial Info
Start Date :
December 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2007
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT01173822
Start Date
December 1 2004
End Date
April 1 2007
Last Update
August 2 2010
Active Locations (1)
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1
Hamilton General Hospital
Hamilton, Ontario, Canada, L8L2X2