Status:

COMPLETED

Impact of Vitamin D Repletion in Hemodialysis Patients

Lead Sponsor:

Mehrotra, Anita, M.D.

Collaborating Sponsors:

National Kidney Foundation, United States

American Heart Association

Conditions:

Vitamin D Deficiency

End-stage Renal Disease

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Dialysis patients often suffer from defects in their immune system (that part of the body which fights infection). Evidence suggests that Vitamin D deficiency may have a negative effect on immunity, a...

Detailed Description

Innate and adaptive immunity are commonly impaired in patients with end stage renal disease (ESRD) on dialysis. The myriad of immune defects in these patients, often attributed to uremia, may account ...

Eligibility Criteria

Inclusion

  • Age \> 18 years
  • Chronic hemodialysis treatments for at least 2 consecutive months
  • 25OH-Vitamin D level \< 25 ng/mL (inclusion criteria for randomization)

Exclusion

  • History of acute renal failure requiring dialysis with potential for renal recovery
  • History of HIV/AIDS
  • Inability to provide informed consent

Key Trial Info

Start Date :

August 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 1 2013

Estimated Enrollment :

116 Patients enrolled

Trial Details

Trial ID

NCT01175798

Start Date

August 1 2010

End Date

August 1 2013

Last Update

September 22 2014

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Mount Sinai School of Medicine

New York, New York, United States, 10029