Status:
COMPLETED
Probiotics and Endotoxemia
Lead Sponsor:
Danisco
Conditions:
Metabolic Endotoxemia
Metabolic Syndrome
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The purpose of this study is to determine whether probiotic treatment of overweight volunteers consuming high fat diet is able to reduce plasma lipopolysaccharide concentration.
Eligibility Criteria
Inclusion
- Body mass index ≥ 27 kg/m2; above 18 years of age
- Used to eat high fat diet (more than 40% of total energy intake)
Exclusion
- Treated cardiovascular risk factors, treated hypertension, treated dyslipidemia, treated diabetes; Known diabetes, hypertension, dyslipidemia
- Severe illnesses
- Artificial heart valve
- Immunosuppression
- Regular consumption of probiotics
- History of bariatric surgery
- Consumption or wish to consume Orlistat
- Participation in other research
- Pregnancy or wishing/trying to get pregnant
- Inability to follow protocol.
Key Trial Info
Start Date :
May 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2011
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT01176942
Start Date
May 1 2010
End Date
May 1 2011
Last Update
December 9 2014
Active Locations (1)
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1
CHU Toulouse Hospital
Toulouse, Cedex 9, France