Status:

COMPLETED

The Role of Gabapentin in Postoperative Pain and Epithelialization After Photorefractive Keratectomy

Lead Sponsor:

Codet Vision Institute

Conditions:

Pain After Photorefractive Keratectomy

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

The primary aims of this study are to determine if treatment with Gabapentin taken systemically (oral tablets) in patients who have photorefractive keratectomy (PRK) surgical treatments reduces post s...

Eligibility Criteria

Inclusion

  • Subjects must be at least 18 years of age
  • Subjects must not have any corneal disease or degeneration
  • Subjects must be candidates for LASIK or PRK refractive surgery

Exclusion

  • History of topical ocular medications within 4 weeks prior to enrollment
  • History of conjunctivitis or ocular inflammation within 4 weeks prior to enrollment
  • History of a previous refractive surgery
  • History of previous diagnosis of corneal disease, degeneration, or glaucoma
  • History of autoimmune disease
  • History of oral anti-histamines currently or within 1 week of study enrollment
  • History of systemic anti-inflammatory or pain medication currently or within 4 weeks of study enrollment
  • Use of oral diuretics or betablocker currently or within 1 week of study enrollment
  • Current diagnosis of dry eye
  • Patients whose Best corrected vision is less than 20/20
  • Patients whose target post operative refraction is not plano
  • Pregnant and lactating

Key Trial Info

Start Date :

April 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 1 2010

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT01177514

Start Date

April 1 2010

End Date

November 1 2010

Last Update

July 29 2015

Active Locations (1)

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Codet Vision Institute

Tijuana, Estado de Baja California, Mexico, 22320