Status:
UNKNOWN
Secondary Prophylaxis of Hepatic Encephalopathy in Cirrhosis
Lead Sponsor:
Govind Ballabh Pant Hospital
Conditions:
Hepatic Encephalopathy
Eligibility:
All Genders
18-75 years
Phase:
PHASE4
Brief Summary
Hepatic encephalopathy (HE), a challenging complication of advanced liver disease, occurs in approximately 30-45% of patients with cirrhosis. The treatment of choice is non-absorbable disaccharides, s...
Detailed Description
Hepatic encephalopathy, a challenging complication of advanced liver disease, occurs in approximately 30-45% of patients with cirrhosis and 10-50% of patients with transjugular intrahepatic portosyste...
Eligibility Criteria
Inclusion
- Patients with cirrhosis and previous history of recovery from hepatic encephalopathy
Exclusion
- history of taking lactulose in the past 6 weeks.
- alcohol intake during the past 6 weeks or during follow up
- patients on secondary prophylaxis for spontaneous bacterial peritonitis
- previous TIPS or shunt surgery
- significant comorbid illness such as heart, respiratory, or renal failure
- any neurologic diseases such as alzheimer's disease, parkinson's disease and nonhepatic metabolic encephalopathies.
Key Trial Info
Start Date :
September 1 2008
Trial Type :
INTERVENTIONAL
End Date :
September 1 2010
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT01178372
Start Date
September 1 2008
End Date
September 1 2010
Last Update
August 10 2010
Active Locations (1)
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1
G B Pant Hospital
New Delhi, National Capital Territory of Delhi, India, 110002