Status:
WITHDRAWN
How Lidocaine Affects Outcomes In Orthopedic Surgery Patients
Lead Sponsor:
Cedars-Sinai Medical Center
Conditions:
General Anesthesia
Surgeries Requiring A Minimum One Day Hospitalization
Eligibility:
All Genders
65+ years
Phase:
PHASE4
Brief Summary
This study will evaluate the effect of intraoperative lidocaine infusion on postoperative orientation and concentration in elderly patients having general anesthesia for orthopedic surgeries requiring...
Detailed Description
Advances in surgical techniques and anesthetic care have resulted in a substantial reduction in peri-operative morbidity and mortality in the elderly. However, post-operative cognitive dysfunction (PO...
Eligibility Criteria
Inclusion
- Scheduled to undergo orthopedic surgery under general anesthesia requiring a minimum two-day hospitalization (e.g. THA, TKA, hardware removal)
- 65 years of age or older
- ASA Physical Classification I - IV
- Willingness and ability to sign an informed consent document
- English-speaking
Exclusion
- Inability to consent or complete cognitive assessments
- Inability to use a PCA system
- Allergy to lidocaine or any other medication administered as part of this protocol
- Emergency surgery
Key Trial Info
Start Date :
June 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2015
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT01179100
Start Date
June 1 2011
End Date
October 1 2015
Last Update
September 7 2015
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Cedars Sinai Medical Center
Los Angeles, California, United States, 90048