Status:
COMPLETED
A Study of Avastin (Bevacizumab) Combined With Chemotherapy in Patients With Metastatic Cancer of the Colon or Rectum
Lead Sponsor:
Hoffmann-La Roche
Conditions:
Colorectal Cancer
Eligibility:
All Genders
18+ years
Phase:
PHASE2
Brief Summary
This study will assess the efficacy and safety of intravenous Avastin in combination with chemotherapy regimens as second-line treatment of metastatic cancer of the colon or rectum. The anticipated ti...
Eligibility Criteria
Inclusion
- Patients with metastatic colon or rectal cancer, progressing or relapsing after first-line treatment;
- Women of childbearing potential must use adequate contraception up to at least 6 months after the last dose of bevacizumab.
Exclusion
- Patients with metastatic colon or rectal cancer scheduled for a first-line systemic treatment;
- Untreated brain metastases, spinal cord compression or primary brain tumours;
- Pregnant or lactating women;
- Major surgical procedure, open biopsy, or significant traumatic injury within 28 days prior to study start;
- Treatment with any investigational drug, or participation in another investigational study, within 30 days prior to enrollment.
Key Trial Info
Start Date :
June 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2010
Estimated Enrollment :
54 Patients enrolled
Trial Details
Trial ID
NCT01181609
Start Date
June 1 2005
End Date
May 1 2010
Last Update
July 28 2014
Active Locations (16)
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1
Angers, France, 49933
2
Besançon, France, 25030
3
Boulogne-Billancourt, France, 92104
4
Colmar, France, 68024