Status:
COMPLETED
Long-Term Impact of Human Papillomavirus (HPV) on Quality of Life
Lead Sponsor:
Memorial Sloan Kettering Cancer Center
Conditions:
Squamous Cell Carcinoma of the Oropharynx
Eligibility:
All Genders
18+ years
Brief Summary
The investigators are doing this study to learn about the quality of life patients have at the end of treatment. Some patients' cancers are related to human papilloma virus or HPV; others are not. HPV...
Eligibility Criteria
Inclusion
- 18 years of age or older
- Diagnosis of squamous cell carcinoma of the oropharynx confirmed by the pathology department at MSKCC
- Completed last treatment for oropharynx cancer (surgery, chemotherapy, or radiation) at least 12 months and no more than 5 years before the date of study enrollment
- Known tumor status or tumor available for HPV testing \[based on chromogenic in situ hybridization with wide spectrum HPV probe (HPV III family 16 probe (Ventana) with affinity to HPV genotypes 16, 18, 31, 33, 35, 45, 51, 52, 56, 58, and 66) or p16 immunohistochemistry done in a Clinical Laboratory Improvement Amendment (CLIA)-approved laboratory; if either of these 2 tests are positive, the patient is classified as positive\].
- Able to speak and read English (study questionnaire-Aim 1 and interview guide-Aim 2 are currently only available in English).
- Received at least one component of treatment for oropharynx cancer at MSKCC or the regional network sites
- If radiation therapy was part of treatment, it must have been delivered at MSKCC or the regional network sites
- For Aim 2 only, diagnosed with an HPV+ oropharynx cancer and have knowledge of this diagnosis prior to study enrollment
Exclusion
- Diagnosed with recurrent disease following completion of primary curative treatment
Key Trial Info
Start Date :
August 1 2010
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 1 2018
Estimated Enrollment :
210 Patients enrolled
Trial Details
Trial ID
NCT01181648
Start Date
August 1 2010
End Date
June 1 2018
Last Update
June 20 2018
Active Locations (6)
Enter a location and click search to find clinical trials sorted by distance.
1
Memoral Sloan Kettering Cancer Center
Basking Ridge, New Jersey, United States
2
Memorial Sloan Kettering Cancer Center @ Suffolk
Commack, New York, United States, 11725
3
Memorial Sloan Kettering West Harrison
Harrison, New York, United States, 10604
4
Memorial Sloan Kettering Cancer Center
New York, New York, United States, 10065