Status:
COMPLETED
Effect of Magnesium Administration in Subjects With Family History of Diabetes or Metabolic Syndrome
Lead Sponsor:
Universita di Verona
Conditions:
Family History of Metabolic Syndrome
Family History of Diabetes
Eligibility:
All Genders
18-50 years
Phase:
PHASE4
Brief Summary
Magnesium is the second most abundant ion in human cells and plays fundamental roles in several enzymatic reactions: it is involved in ATP production, in the phosphorylation of proteins, in glucose me...
Eligibility Criteria
Inclusion
- positive family history of type II diabetes mellitus and/or metabolic syndrome(AHA/NHLBI criteria).
Exclusion
- any therapy related to metabolic syndrome (that is antihypertensive, anti diabetic, antilipemic drugs);
- age \< 18 years or \>50 years;
- previously diagnosed hypertension or immediate need for antihypertensive therapy (BP≥160/100);
- diabetes mellitus (ADA criteria);
- obesity (BMI\>30Kg/m2);
- Continuative use of NSAIDs, magnesium or vitamin supplements;
- Hypermagnesaemia;
- Previous cardio- or cerebrovascular events;
- chronic kidney or liver or inflammatory or neoplastic disease;
- gastrointestinal dysfunction with hypomotility;
- active smoke (\>5 cigarettes per day);
- Impossibility to give informed consent.
Key Trial Info
Start Date :
February 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2012
Estimated Enrollment :
14 Patients enrolled
Trial Details
Trial ID
NCT01181830
Start Date
February 1 2010
End Date
December 1 2012
Last Update
October 16 2013
Active Locations (1)
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1
Azienda Ospedaliera Universitaria Integrata - Division of Internal Medicine C
Verona, VR, Italy, 37134