Status:
UNKNOWN
Physical Exercise as a Targeted Therapy in Patients With Chronic Rheumatic Muscle Inflammation
Lead Sponsor:
Karolinska Institutet
Collaborating Sponsors:
Uppsala University Hospital
Sahlgrenska University Hospital
Conditions:
Myositis
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
The objectives of this study are to test if hypoxia in muscle tissue is an important factor contributing to clinical symptoms in chronic rheumatic muscle inflammation and to evaluate if a 12 week endu...
Eligibility Criteria
Inclusion
- Patients with chronic, stable polymyositis or dermatomyositis with diagnosis of definite or probable polymyositis or dermatomyositis (Bohan and Peter 1975)
- Age 18-80 years
- Duration since diagnosis \> 6 months
- Exercising \< once a week,
- Stable disease activity and medication for at least one month.
- Ten healthy controls matched for age, gender and physical exercise level will be included.
- \-
Exclusion
- Severe pulmonary fibrosis
- Heart or lung conditions that contraindicate vigorous exercise
- Severe osteoporosis
- Not being able to perform the exercise program.
Key Trial Info
Start Date :
January 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 1 2012
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT01184625
Start Date
January 1 2008
End Date
August 1 2012
Last Update
June 27 2011
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Rheumatology unit, Karolinska University Hospital
Stockholm, Sweden