Status:

COMPLETED

The Effects of Efalex Active 50+ on Cognitive Performance, Well-being and Cerebral Hemodynamics in Healthy Older Adults

Lead Sponsor:

Northumbria University

Collaborating Sponsors:

Efamol Ltd

Conditions:

Cognitive Function

Mood

Eligibility:

All Genders

50-70 years

Phase:

NA

Brief Summary

Dietary intake of omega-3 polyunsaturated fatty acids (n-3 PUFAs) is inversely associated with cognitive decline and dementia (e.g. Kalmijn et al. 2004, Heude et al. 2003, Morris et al. 2005, Dullemei...

Eligibility Criteria

Inclusion

  • Generally healthy
  • Aged 50-70 years
  • Low consumer of oily fish (≤ 1 portion/month)
  • Has not taken vitamin/herbal supplements in the past 3 months
  • Has not taken omega-3 supplement (including cod liver oil) in the past 2 years
  • Has a good level of written and spoken English
  • Has an MMSE score \> 24
  • Is suffering from a memory complaint (MAC-Q score \> 24)

Exclusion

  • BMI \> 35
  • Smokes more than 15 cigarettes per day
  • History of alcohol/drug abuse
  • Currently taking statins/antidepressant/blood thinning medication
  • Has high blood pressure
  • Suffers from migraines/anaemia/heart or lung disorder/diabetes/active infections/jaundice/haemophilia or other clotting disease
  • Has learning difficulties/dyslexia/colour blindness
  • Is HIV positive
  • Has hepatitis

Key Trial Info

Start Date :

July 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2012

Estimated Enrollment :

261 Patients enrolled

Trial Details

Trial ID

NCT01185379

Start Date

July 1 2010

End Date

June 1 2012

Last Update

September 26 2012

Active Locations (1)

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1

Northumbria University

Newcastle upon Tyne, Tyne and Wear, United Kingdom, NE1 8ST