Status:
COMPLETED
Statin Contrast Induced Nephropathy Prevention
Lead Sponsor:
Centro Cardiopatici Toscani
Conditions:
Acute Coronary Syndrome
Eligibility:
All Genders
18-90 years
Phase:
PHASE4
Brief Summary
This open-label study, prospective, randomized trial evaluating the acute (in-hospital) pleiotropic and clinical effects of a hydrophilic statin (rosuvastatin) in patients with acute coronary syndrome
Detailed Description
The primary purpose of this study is to determine whether, in patients with acute coronary syndromes not taking statins in chronic administration, high doses of a hydrophilic statin (rosuvastatin) adm...
Eligibility Criteria
Inclusion
- Are eligible for the study all patients admitted to CCU for Acute Coronary Syndrome without ST elevation (NSTEMI) candidates for early invasive strategy (coronary angiography within 48 hours from the admission) and without previous therapy with statins.
Exclusion
- inability to provide consent
- pregnancy or lactation
- intolerance to statins
- therapy with other lipid lowering drugs
- acute or chronic liver disease
- chronic muscle disease
- acute renal failure or chronic renal failure stage IV
- neoplastic
- exposure to iodinated contrast medium in the previous 10 days
Key Trial Info
Start Date :
July 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2012
Estimated Enrollment :
500 Patients enrolled
Trial Details
Trial ID
NCT01185938
Start Date
July 1 2010
End Date
October 1 2012
Last Update
October 19 2012
Active Locations (1)
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1
Cardiology Division, Prato Hospital
Prato, Prato, Italy, 59100