Status:
WITHDRAWN
Early Noninvasive Positive Pressure Ventilation in Children With Status Asthmaticus
Lead Sponsor:
Southern Illinois University
Conditions:
Status Asthmaticus
Eligibility:
All Genders
1-18 years
Phase:
PHASE1
Brief Summary
Status asthmaticus is recognized as a common cause of morbidity in children in the United States. In recent years, hospitalization rates have reached an all time high. This study will evaluate the saf...
Detailed Description
Status asthmaticus is defined as severe asthma that fails to respond to inhaled short acting β agonists (SABA), oral or intravenous steroids, and oxygen, leading to hospital admission for further mana...
Eligibility Criteria
Inclusion
- children, 1- 18 years of age, with a known history of asthma admitted to the PICU at St John's Children's Hospital with status asthmaticus
- clinical asthma score (CAS) between 3 - 8 after receiving one dose of systemic steroid, 1 hour of continuous albuterol (SABA), and 3 doses of ipratropium bromide
- written informed consent from the patient's parent or legal guardian
Exclusion
- no previous history of asthma,
- absence of airway protective reflexes,
- absence of respiratory drive,
- excessive oral secretions,
- need for emergent intubation as determined by the attending physician,
- facial or airway anomaly or injury precluding the use of tight fitting mask
Key Trial Info
Start Date :
January 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2010
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT01188473
Start Date
January 1 2009
End Date
January 1 2010
Last Update
December 19 2014
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Southern Illinois University School of Medicine
Springfield, Illinois, United States, 62794-9676