Status:
COMPLETED
Preoperative Single-dose Steroid Application for the Treatment of Nausea and Vomiting After Thyroid Surgery
Lead Sponsor:
Cantonal Hospital of St. Gallen
Conditions:
Thyroidectomy
Thyroid Diseases
Eligibility:
All Genders
18+ years
Phase:
PHASE3
Brief Summary
The study is to compare the postoperative recovery, as determined by postoperative nausea and vomiting (PONV) after preoperative application of single-dose dexamethasone versus saline in patients unde...
Eligibility Criteria
Inclusion
- Age \> 18
- Planned partial or total thyroidectomy
Exclusion
- History of adverse effects to dexamethasone or propyleneglycol or di-natrium-EDTA
- Patients with chronic pain
- Necessity for opioids-application in the postoperative course
- Not possible administration of a cervical block (0.5% bupivacaine at a dose of 20ml)
- Patients with Diabetes mellitus
- Pregnancy (test in young women)
- Glaucoma
- Patients who received antiemetic therapy within 48h before surgery
- Patients with acute pain requiring painkillers others than paracetamol or more than single dose NSAR treatment within 48h before surgery
- Use of psychotropic drugs
- Incompliant patients
- Preoperatively high suspicion of malignancy
- Re-operations
Key Trial Info
Start Date :
January 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2013
Estimated Enrollment :
152 Patients enrolled
Trial Details
Trial ID
NCT01189292
Start Date
January 1 2011
End Date
June 1 2013
Last Update
July 7 2015
Active Locations (1)
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1
Department of Surgery
Sankt Gallen, Switzerland, 9007