Status:
COMPLETED
Cellular and Molecular Characterization of the Immune Response in Healthy NIH Employees atBaseline, and After Immunization With the H1N1 or Seasonal Influenza Vaccines
Lead Sponsor:
National Heart, Lung, and Blood Institute (NHLBI)
Conditions:
Healthy Volunteers
Influenza
Eligibility:
All Genders
18+ years
Brief Summary
Background: \- Seasonal influenza is a major health problem whose impact is typically reduced by vaccination. The H1N1 (swine flu) influenza virus is an emerging pathogen that has the potential to ca...
Detailed Description
Seasonal influenza is a major health problem whose impact is typically reduced by vaccination. The H1N1 (swine flu) influenza virus is an emerging pathogen which has the potential to cause devastating...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA:
- NIH employees scheduled to receive the Influenza and H1N1 vaccines through OMS.
- Health status confirmed by History, Physical Exam and blood work through the CHI Screening Protocol.
- Age 18 years and older (no upper limit).
- Able to comprehend the investigational nature of the protocol and provide informed consent.
- EXCLUSION CRITERIA:
- Recipient of another vaccine or immune modulating drug within 6 months prior to study entry.
- Severe allergies to eggs or their products.
- Prior severe reactions to vaccines.
- Participation on any blood collection or blood donation procedure during study participation.
- Current pregnancy (women of child bearing potential must have a negative serum pregnancy test done on screening within 1 week of protocol accrual).
Exclusion
Key Trial Info
Start Date :
September 18 2009
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
Estimated Enrollment :
203 Patients enrolled
Trial Details
Trial ID
NCT01191853
Start Date
September 18 2009
Last Update
January 8 2026
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
National Institutes of Health Clinical Center
Bethesda, Maryland, United States, 20892