Status:
COMPLETED
A Comparison of p53-induced Genes Activation in Patients With and Without Acute Myocardial Infarction
Lead Sponsor:
Meir Medical Center
Conditions:
Acute Myocardial Infarction
Eligibility:
MALE
18+ years
Brief Summary
The purpose of this study is to compare p53-induced genes activation as possible markers differentiating between patients presenting with acute myocardial infarction and controls.
Detailed Description
The diagnosis of acute myocardial infarction is based on the rise of bio-markers for cardiac necrosis such as troponin. While troponin measurement is highly sensitive for myocardial necrosis it has se...
Eligibility Criteria
Inclusion
- Acute MI group:
- Patient presenting with chest pain lasting for at leasY 1 hour and no more than 6 hours accompanied by 1 of the following ECG criteria:
- ST segment elevation of anterior or inferior wall (at least 2 consecutive leads)
- New LBBB
- Controls:
- Patients undergoing non-invasive evaluation of possible myocardial ischemia
Exclusion
- Chronic lung disease requiring chronic treatment
- Any malignancy in the 5 year prior to enrollment
Key Trial Info
Start Date :
November 1 2010
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
October 1 2011
Estimated Enrollment :
79 Patients enrolled
Trial Details
Trial ID
NCT01191879
Start Date
November 1 2010
End Date
October 1 2011
Last Update
October 31 2012
Active Locations (1)
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1
Meir Medical Center
Kfar Saba, Israel, Israel