Status:
COMPLETED
Biomakers in Tissue Samples From Patients With Recurrent and/or Metastatic Squamous Cell Cancer of the Head and Neck Previously Treated With Cisplatin With or Without Cetuximab
Lead Sponsor:
ECOG-ACRIN Cancer Research Group
Collaborating Sponsors:
National Cancer Institute (NCI)
Conditions:
Head and Neck Cancer
Eligibility:
All Genders
18-120 years
Brief Summary
RATIONALE: Studying samples of tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. PURPOSE: This ...
Detailed Description
OBJECTIVES: * To investigate the association between ERCC1 expression and clinical outcomes (response rate, progression-free survival, and overall survival) in patients with recurrent and/or metastat...
Eligibility Criteria
Inclusion
- DISEASE CHARACTERISTICS:
- Diagnosis of squamous cell carcinoma of the head and neck
- Recurrent and/or metastatic disease
- Received cisplatin with or without cetuximab on clinical trial ECOG-E5397
- Slides and blocks of tumor specimens available
- PATIENT CHARACTERISTICS:
- Not specified
- PRIOR CONCURRENT THERAPY:
- See Disease Characteristics
Exclusion
Key Trial Info
Start Date :
August 5 2010
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
October 5 2010
Estimated Enrollment :
79 Patients enrolled
Trial Details
Trial ID
NCT01192750
Start Date
August 5 2010
End Date
October 5 2010
Last Update
May 17 2017
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