Status:
COMPLETED
Albumin Kinetics in Generalized Inflammation
Lead Sponsor:
Karolinska Institutet
Collaborating Sponsors:
Karolinska University Hospital
Region Stockholm
Conditions:
Major Abdominal Surgery
Eligibility:
All Genders
40+ years
Phase:
PHASE4
Brief Summary
The purpose of this study is to determine whether the kinetics of endogenous albumin is altered by the generalized inflammation caused by major abdominal surgery.
Detailed Description
Albumin infusions have been used for expansion of the plasma volume for more than 60 years, not only in the operating room, but also in trauma and sepsis. However, there is an ongoing debate whether a...
Eligibility Criteria
Inclusion
- written informed consent
- patients planned for major abdominal surgery, pancreatic
- age ≥ 40 years
Exclusion
- pregnant or lactating patients
- planned peri-operative infusions of albumin or plasma
- S-creatinine \> 110 mmol/L
- allergy against iodine
- other conditions preventing the subject from participating in the study, as judged by the investigator
Key Trial Info
Start Date :
September 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2010
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT01194492
Start Date
September 1 2010
End Date
December 1 2010
Last Update
January 19 2021
Active Locations (1)
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1
Karolinska University Hosptial, Huddinge
Stockholm, Sweden, SE-141 86