Status:

TERMINATED

Endothelial Function Study Before Cardiovascular Surgery

Lead Sponsor:

University Hospital, Grenoble

Conditions:

Chronic Obstructive Pulmonary Disease (COPD)

Obstructive Sleep Apnea Syndrome (OSAS)

Eligibility:

All Genders

18-80 years

Brief Summary

The aim of this clinical trial is to evaluate the effect of chronic obstructive pulmonary disease (COPD) and/or obstructive sleep apnea syndrome (OSAS) on the endothelial function, before cardiovascul...

Detailed Description

Secondary objectives of this clinical trial : * To evaluate the effect of COPD and/or OSAS on the systemic inflammation, insulin-resistance and oxydative stress, in comparison with non COPD non OSAS ...

Eligibility Criteria

Inclusion

  • Men or women between 18 and 80 years old
  • Patient with planned coronary artery bypass graft surgery
  • Patient with planned peripheral vascular surgery
  • Patient with aortic surgery

Exclusion

  • Patient with aortic or mitral valvular replacement
  • Patient with emergency peripheral valvular surgery
  • Patient with emergency coronary artery bypass graft surgery
  • Patient with evolutive malignancy disease
  • Pregnant or lactating women
  • Patient with inadvisable bronchodilator (used for functional respiratory) exploration

Key Trial Info

Start Date :

April 1 2010

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

November 30 2018

Estimated Enrollment :

109 Patients enrolled

Trial Details

Trial ID

NCT01195064

Start Date

April 1 2010

End Date

November 30 2018

Last Update

September 27 2022

Active Locations (3)

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Page 1 of 1 (3 locations)

1

University Hospital of Angers

Angers, France, 49033

2

Mutualist Hospital group

Grenoble, France, 38000

3

University Hospital of Grenoble

Grenoble, France, 38043