Status:

UNKNOWN

MEDIR Medulloblastome

Lead Sponsor:

University Hospital, Grenoble

Conditions:

Child Cancer Brain

Eligibility:

All Genders

8-12 years

Brief Summary

The medulloblastome is a tumour of the child relatively frequent usually sitting in the cerebellum and treated by surgery, radiotherapy and chemotherapy. After the treatment, these children present co...

Detailed Description

The functional study should make it possible to show the specifically committed networks according to the cognitive tasks. Among patients, the relative difficulty to carry out the tasks of working mem...

Eligibility Criteria

Inclusion

  • Old from 8 to 12 years
  • Total IQ \> 70 for the participation in the study and/or age développemental 7 years minimum
  • Treaties for a médulloblastome after the 6 years age in remission supplements with 6 months a minimum time compared to the end of all the treatments
  • Followed within the framework of the protocol of evaluation of the mnemic and attentionnelles after-effects
  • Sensory after-effects compatible with the realization of the tasks and good performances at the time of the preceding drive the IRM
  • Absence of counter-indication to the IRM
  • Absence of catch of méthylphénidate (Ritaline®) for the treatment of disorders attentionnels 48h before the IRM
  • Enlightened assent signed by at least one of the two parents or holders of the parental authority and by the child (minor)

Exclusion

  • Agitation or movements of the head at the time the IRM
  • Artifacts of magnetic susceptibility in projection of the areas of interest (intracranial haemorrhage, cortical and/or metal remains post-operative) • Bad execution of the cognitive tasks
  • Tumoral relapse in the course of protocol

Key Trial Info

Start Date :

October 1 2007

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

July 1 2012

Estimated Enrollment :

80 Patients enrolled

Trial Details

Trial ID

NCT01197924

Start Date

October 1 2007

End Date

July 1 2012

Last Update

September 9 2010

Active Locations (8)

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Page 1 of 2 (8 locations)

1

University hospital

Bordeaux, Bordeaux, France, 33076

2

Institut d'Hématologie et d'Oncologie Pédiatrique

Lyon, Lyon, France, 69008

3

Hôpital Frédéric Joliot Orsay - Hôpital Necker

Paris, Paris, France, 75015

4

Institut Curie

Paris, Paris, France, 75231