Status:

COMPLETED

The Effects of Dexmedetomidine and Propofol on Cerebral Blood Flow and Brain Oxygenation During Deep Brain Stimulation

Lead Sponsor:

The Cleveland Clinic

Conditions:

Intracranial Neurosurgery

Eligibility:

All Genders

18-80 years

Phase:

NA

Brief Summary

The investigators will evaluate the effects of dexmedetomidine and propofol on cerebral blood flow and brain oxygenation during Deep Brain Stimulation (DBS) surgery. Specifically, the investigators wi...

Eligibility Criteria

Inclusion

  • ASA I-III.
  • Scheduled for DBS.

Exclusion

  • History of dystonia.
  • Severe heart failure with ejection fraction less than 30%.
  • History of obstructive sleep apnea.
  • History of renal failure with creatinine level \> 2 mg/dl.
  • Allergies to α-2 agonists and propofol.
  • Current use of α-2 agonist medications such as clonidine.

Key Trial Info

Start Date :

October 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 1 2013

Estimated Enrollment :

44 Patients enrolled

Trial Details

Trial ID

NCT01200433

Start Date

October 1 2010

End Date

August 1 2013

Last Update

December 14 2016

Active Locations (1)

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1

Cleveland Clinic Foundation

Cleveland, Ohio, United States, 44195