Status:
UNKNOWN
Study of Administration Of Antithrombin in Patients With Low Plasmatic Levels of Antithrombin After Cardiac Surgery
Lead Sponsor:
University of Bari
Conditions:
Aortic Valve Insufficiency
Aortic Valve Stenosis
Eligibility:
All Genders
18-80 years
Phase:
PHASE4
Brief Summary
General and specific objectives of the search: evaluate the effects of the administration of Antithrombin III (ATIII) on the activation of the coagulation system and of the fibrinolysis, platelet func...
Eligibility Criteria
Inclusion
- All patients were candidates for cardiac surgery intervention in extracorporeal circulation
Exclusion
- positive history for allergic reactions to AT III
- cardiac surgery "Off-Pump"
- administration of AT during surgery or within 48 h
- treatment with drugs and non-steroidal steroids within 48 h prior
- disorders of coagulation
- platelets \<30,000
- pre-existing IRC in dialysis treatment
- severe liver failure
- enlistment in another trial in the last 30 days
- hypothermia
- emergency
- reopening
- length of CEC\> 180 minutes
- subjects incapable of giving legal consent
Key Trial Info
Start Date :
September 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
November 1 2011
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT01201070
Start Date
September 1 2009
End Date
November 1 2011
Last Update
September 15 2010
Active Locations (1)
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1
Azienda Ospedaliero-Universitaria Policlinico
Bari, Italy, 70124