Status:
COMPLETED
Cost-effectiveness Study of miRview™ Mets in Patients With Cancer of Unknown Primary (CUP)
Lead Sponsor:
Teva Branded Pharmaceutical Products R&D, Inc.
Collaborating Sponsors:
Clalit Health Services
Rosetta Genomics
Conditions:
Neoplasms, Unknown Primary
Eligibility:
All Genders
18+ years
Brief Summary
The aim of the study is in cancer of unknown primary (CUP) patients, to compare the cost-effectiveness of miRview™ mets test with conventional work-up in identifying the primary tumor site.
Detailed Description
Thousands of patients are diagnosed each year with metastatic cancer; however, about 3-5% of them are diagnosed with Cancer of Unknown Primary (CUP). In order to identify the optimal treatment plan fo...
Eligibility Criteria
Inclusion
- Patients who present with histologically-confirmed metastatic cancer in whom an initial work-up which consists of detailed medical history, physical examination, basic laboratory studies, histopathological review of biopsy material, and CT scan of the chest abdomen and pelvis fail to identify the primary site.
- Older than 18 years
- Performance status \<2
- life expectancy \>3 months
- ANC \>1500
- Platelets \>100,000 if bone marrow is not involved
- Hb \> 9
- Creatinine \<2
- LFTS \< x5 normal
- Histology proven of malignancy
- Enough material for miRview test (10 slices of 10 micrometer sections)
- Member of Clalit HMO
Exclusion
- Patients unable or unwilling to sign the informed consent form
- Under 18 years old
- Performance status \>2
- life expectancy\<3 months
- ANC \<1500
- Platelets \<100,000 if marrow not involved
- Hb \< 9
- Creatinine \>2
- LFTS \> x5 normal
- Not member of Clalit HMO
Key Trial Info
Start Date :
May 1 2010
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
April 1 2012
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT01202786
Start Date
May 1 2010
End Date
April 1 2012
Last Update
August 15 2012
Active Locations (3)
Enter a location and click search to find clinical trials sorted by distance.
1
Ha'emek Medical Center
Afula, Israel
2
Soroka Medical Center
Beersheba, Israel
3
Rabin Medical Center
Petah Tikva, Israel, 49100