Status:

COMPLETED

Early Short-term Antibiotic Therapy in Penetrating Abdominal Trauma, 3 vs 7 Days

Lead Sponsor:

Silvia M. Pinango L.

Collaborating Sponsors:

Merck Sharp & Dohme LLC

Conditions:

SURGICAL SITE INFECTION

Eligibility:

All Genders

12-65 years

Phase:

PHASE2

PHASE3

Brief Summary

Abdominal penetrating trauma represents a frequent cause of consult into emergency rooms in Venezuela. Accidents and violence at Hospital "Miguel Perez Carreño" along april 2009 were represented by gu...

Detailed Description

General objectives The object of this research is to evaluated the impact of Early short-term antibiotic therapy with Ertapenem, 3 vs 7 days, upon clinical postoperatory evolution in patients with pen...

Eligibility Criteria

Inclusion

  • Patients with penetrating abdominal trauma who attended the emergency room within 12 hours after trauma, admitted to an exploratory laparotomy.
  • Patients aged 12 to 65 years.

Exclusion

  • Clinical history of immunologic diseases, cancer, use of immunosuppressors, steroids, malnutrition, morbid obesity.
  • Concomitant pathology at admittance: urinary infections, respiratory infections, hepatitis, viral diseases.
  • Associated open bone fractures.
  • Patients with hemodynamic instability during pre or peroperative.

Key Trial Info

Start Date :

December 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 1 2011

Estimated Enrollment :

56 Patients enrolled

Trial Details

Trial ID

NCT01203046

Start Date

December 1 2010

End Date

October 1 2011

Last Update

August 10 2012

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