Status:

WITHDRAWN

Exploratory Study of Farletuzumab to Treat Resectable, Non-functioning Pituitary Adenomas

Lead Sponsor:

Morphotek

Conditions:

Resectable, Non-functioning Pituitary Adenoma

Eligibility:

All Genders

18+ years

Phase:

PHASE2

Brief Summary

The purpose of this study is to evaluate whether therapy with farletuzumab is effective and safe in the treatment of resectable, non-functioning pituitary adenomas.

Detailed Description

Non-functioning pituitary adenomas are the most frequent type of pituitary tumors, defined by the lack of hormonal overproduction from the tumor. Non-functioning macroadenomas are \> 1 cm in size that...

Eligibility Criteria

Inclusion

  • Males and females \>18 years old
  • Diagnosis of non-functional pituitary adenoma
  • Able and willing to undergo surgical resection of the pituitary tumor
  • Significant medical conditions must be well-controlled and stable for at least 30 days prior to signing the informed consent form

Exclusion

  • Presence of clinically significant pituitary apoplexy
  • Presence of hormone-secreting adenomas
  • Presence of compressive optic neuropathy due to pituitary tumor
  • No prior surgical, medical, or radiation therapy in the last 6 months

Key Trial Info

Start Date :

February 1 2011

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 1 2013

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT01203618

Start Date

February 1 2011

End Date

August 1 2013

Last Update

November 4 2013

Active Locations (1)

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1

Emory University

Atlanta, Georgia, United States, 30322