Status:
COMPLETED
Lorazepam, Diphenhydramine Hydrochloride, and Haloperidol Gel in Healthy Volunteers
Lead Sponsor:
Virginia Commonwealth University
Collaborating Sponsors:
National Cancer Institute (NCI)
American Cancer Society, Inc.
Conditions:
Healthy
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
RATIONALE: Lorazepam, diphenhydramine hydrochloride, and haloperidol gel, when absorbed into the skin, may be an effective treatment for nausea and vomiting.PURPOSE: This clinical trial studies loraze...
Detailed Description
OBJECTIVES:I. To study the absorption of the three components in the topical ABH gel in 10 healthy volunteers, and determine if there are any adverse effects. OUTLINE: Patients apply lorazepam, diphen...
Eligibility Criteria
Inclusion
- Completed a medical screening questionnaire
- English speaking
- No allergies to the drugs
- Able to complete the forms
- If a woman of childbearing age, agree to use contraception
Exclusion
- History of substance abuse, psychiatric disorder, acquired brain injury, the possibility of pregnancy (not using birth control, and of child bearing age)
- Use of any medication that would contraindicate benzodiazepine administration
- Pregnant or nursing
Key Trial Info
Start Date :
November 15 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 17 2011
Estimated Enrollment :
11 Patients enrolled
Trial Details
Trial ID
NCT01204255
Start Date
November 15 2010
End Date
May 17 2011
Last Update
November 17 2017
Active Locations (1)
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1
Virginia Commonwealth University/Massey Cancer Center
Richmond, Virginia, United States, 23298