Status:

TERMINATED

Efficacy and Safety of Liraglutide in Subjects With Type 1 Diabetes Undergoing Islet Cell Transplantation

Lead Sponsor:

Novo Nordisk A/S

Conditions:

Diabetes

Diabetes Mellitus, Type 1

Eligibility:

All Genders

18+ years

Phase:

PHASE2

Brief Summary

This trial is conducted in Europe and North America. The aim of this trial is to investigate if liraglutide treatment can increase the proportion of insulin-independent subjects one year after islet c...

Eligibility Criteria

Inclusion

  • Type 1 diabetes mellitus for at least 5 years
  • Candidate for islet cell transplantation based upon local accepted practice and guidelines
  • Reduced awareness of hypoglycaemia

Exclusion

  • Treatment with any anti-diabetic medication other than insulin including insulin pump within 4 weeks of trial start
  • Any previous organ transplantation
  • A history of acute idiopathic or chronic pancreatitis
  • Family or personal history of multiple endocrine neoplasia type 2 (MEN2) or familial medullary thyroid carcinoma (FMTC)

Key Trial Info

Start Date :

March 21 2012

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 3 2013

Estimated Enrollment :

3 Patients enrolled

Trial Details

Trial ID

NCT01206101

Start Date

March 21 2012

End Date

June 3 2013

Last Update

March 30 2017

Active Locations (16)

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Page 1 of 4 (16 locations)

1

Novo Nordisk Investigational Site

Duarte, California, United States, 91010

2

Novo Nordisk Investigational Site

Chicago, Illinois, United States, 60612

3

Novo Nordisk Investigational Site

Boston, Massachusetts, United States, 02114

4

Novo Nordisk Investigational Site

Madison, Wisconsin, United States, 53792-0001