Status:

COMPLETED

The Effect of HIV Tat Protein on HCV Replication in an In-vitro Model System

Lead Sponsor:

George Washington University

Conditions:

Human Immunodeficiency Virus (HIV)

Hepatitis C, Chronic

Eligibility:

All Genders

18+ years

Brief Summary

Investigators in the Division of Infectious Diseases and the Departments of Biochemistry and Molecular Biology of The George Washington University Medical Center are carrying out a research study to d...

Detailed Description

Samples will be collected from 4 groups of patients with HIV/HCV infection, identified by the virologic control of either HIV, HCV, or both. Sera will be used in an in-vitro hepatocyte model of hepati...

Eligibility Criteria

Inclusion

  • Meets one of the following criteria:
  • detectable HIV RNA and detectable HCV RNA
  • undetectable HIV RNA (treated) and detectable HCV RNA
  • undetectable HIV RNA (treated) and undetectable HCV RNA
  • undetectable HCV RNA (mono-infected)
  • detectable HCV RNA (mono-infected)
  • detectable HIV RNA (mono-infected)
  • Participants will be men and women, ages 18 and older, and who are patients being seen in the clinics of the Medical Faculty Associates, and meet the above criteria.

Exclusion

  • None

Key Trial Info

Start Date :

July 1 2010

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

June 1 2015

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT01206933

Start Date

July 1 2010

End Date

June 1 2015

Last Update

February 10 2016

Active Locations (1)

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George Washington University Medical Faculty Associates

Washington D.C., District of Columbia, United States, 20037

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