Status:
COMPLETED
An Arrhythmia Risk Stratification and Genetic Trial
Lead Sponsor:
University Medical Center Goettingen
Collaborating Sponsors:
UMC Utrecht
KU Leuven
Conditions:
Cardiomyopathies, Primary
Arrhythmia
Eligibility:
All Genders
18+ years
Brief Summary
The prospective EUTrigTreat multi-center study is an observational, advanced diagnostics and genetic risk stratification trial in patients with standard indications for ICD treatment, with and without...
Detailed Description
An increasing number of patients receive implantable cardioverter-defibrillators for primary and secondary prevention of sudden cardiac death. Within this group, it is difficult to differentiate betwe...
Eligibility Criteria
Inclusion
- Standard indication for ICD treatment according to ACC/AHA/ESC guidelines for primary or secondary prevention of SCD
- Age ≥ 18 years
- Nonischemic cardiomyopathies: DCM, HCM/HOCM, ARVC or
- Channelopathies: Brugada, LQT, CPVT or
- Idiopathic VT/VF or
- Diffuse coronary artery disease, without transmural myocardial infarction in history (ACS and NSTEMI with CK maximum of 400 U/l allowed)
Exclusion
- Unstable cardiac disease
- PCI or CABG \< 3 months ago
- Implantation of a CRT device \< 6 months ago
- ICD unable to deliver programmed ventricular stimulation via programmer (only in the noninvasive EP study group)
- Women of childbearing potential in case of positive pregnancy test at the time of enrollment
Key Trial Info
Start Date :
January 1 2010
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
September 1 2014
Estimated Enrollment :
672 Patients enrolled
Trial Details
Trial ID
NCT01209494
Start Date
January 1 2010
End Date
September 1 2014
Last Update
December 2 2015
Active Locations (4)
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1
Katholieke Universiteit Leuven, Dept. of Cardiology
Leuven, Belgium, 3000
2
University Medical Center Goettingen, Dept. of Cardiology and Pneumology
Göttingen, Germany, 37075
3
Attikon Hospital University of Athens, BRFAA, Dept. of Cardiology
Athens, Greece, 17151
4
Universitair Medisch Centrum Utrecht, Depts. of Cardiology and Physiology
Utrecht, Netherlands, 3584 CM