Status:

UNKNOWN

Retinal Vascular Reactivity in Subjects With Newly Diagnosed Glaucoma Before and After Selective Laser Trabeculoplasty

Lead Sponsor:

University of Toronto

Collaborating Sponsors:

University of Western Ontario, Canada

Conditions:

Glaucoma

Eligibility:

All Genders

40-75 years

Brief Summary

The purpose of this study is to assess retinal blood flow and vascular reactivity in patients with newly diagnosed primary open angle glaucoma pre- and post-primary Selective Laser Trabeculoplasty(SLT...

Detailed Description

We previously found that vascular reactivity improved after short term treatment with dorzolamide drops. It is not clear whether this improvement was a direct effect of the medication or secondary eff...

Eligibility Criteria

Inclusion

  • Age 40-75 years (Male or Female)
  • Best corrected visual acuity of at least 20/40
  • No previous treatment for glaucoma
  • Ametropia less than ±6.0 DS and ±2.5 DC)
  • Non-smoker
  • No cardiovascular/respiratory disorders

Exclusion

  • Past history of diabetes and cerebrovascular accident
  • Vascular occlusive disease affecting the ocular circulation such as: diabetic retinopathy, retinal vein occlusion and retinal artery occlusion
  • Previous intraocular surgery
  • Ocular media opacities limiting the use of the imaging tests

Key Trial Info

Start Date :

November 1 2008

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

Estimated Enrollment :

12 Patients enrolled

Trial Details

Trial ID

NCT01209975

Start Date

November 1 2008

Last Update

September 28 2010

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Toronto Western Hospital

Toronto, Ontario, Canada, M5T2S8