Status:

RECRUITING

Characterization of the Mechanisms of Resistance to Azacitidine

Lead Sponsor:

Centre Hospitalier Universitaire de Nice

Conditions:

Myelodysplastic Syndromes or Acute Myeloid Leukemia With Multilineage Dysplasia

Eligibility:

All Genders

18+ years

Brief Summary

Myelodysplastic syndromes (MDS) are frequent diseases in elderly patients (median age: 71 years). IPSS classification defines low risk (Low and Intermediate 1), and high risk (Intermediate 2 and High)...

Eligibility Criteria

Inclusion

  • Age ≥ 18 years
  • High Risk or Intermediate 2 MDS (IPSS)
  • AML-MD (WHO classification)
  • Treatment with minimum three to six cycles of Azacitidine
  • Informed consent form signed

Exclusion

  • Treatment with others chemotherapies alone or in association

Key Trial Info

Start Date :

September 1 2010

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

September 1 2025

Estimated Enrollment :

250 Patients enrolled

Trial Details

Trial ID

NCT01210274

Start Date

September 1 2010

End Date

September 1 2025

Last Update

March 19 2025

Active Locations (4)

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Page 1 of 1 (4 locations)

1

CH d'Antibes

Antibes, France

2

CHU de Nice - Hôpital de l'Archet

Nice, France, 06200

3

Centre Antoine Lacassagne

Nice, France

4

CH Princesse Grace

Monaco, Monaco