Status:
COMPLETED
Effects of the Variation in the Time of Systemic Administration of Metronidazole and Amoxicillin Associated to the Non-surgical Therapy of Chronic Periodontitis.
Lead Sponsor:
University of Chile
Collaborating Sponsors:
Colgate Palmolive
Conditions:
Chronic Periodontitis
Clinical and Microbiological Effects
Eligibility:
All Genders
35-65 years
Phase:
PHASE4
Brief Summary
• Background: Peridontitis is a group of diseases with complex bacterial etiology that affects a large proportion of the Chilean and worldwide population. Its treatment, based on an anti-infective mec...
Eligibility Criteria
Inclusion
- a) age of 35 years old or more, b) at least 3 molars in the mouth, c) at least one site in three of the four quadrants with clinical attachment loss ≥ 3mm; d) at least 4 sites in different teeth with probing depth and clinical attachment level ≥ 6mm and bleeding on probing and at least 14 tooth present in the mouth
Exclusion
- a) previous professional root planning; b) systemic/topic antibiotic or antiinflammatory treatment, at least 6 months prior to the initiation of the study; c) immunosuppression or need for antibiotic coverage for routine dental therapy; d) systemic condition that could affect the progression of periodontal disease (diabetes); e) pregnancy or lactation; e) allergy or intolerance to metronidazole or amoxicillin; f) smokers
Key Trial Info
Start Date :
January 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2014
Estimated Enrollment :
42 Patients enrolled
Trial Details
Trial ID
NCT01211223
Start Date
January 1 2010
End Date
March 1 2014
Last Update
June 16 2016
Active Locations (1)
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1
Facultad de Odontologia
Santiago, R Metropolitana, Chile, Santiago