Status:

COMPLETED

Acetaminophen Transfer Across the Placenta and the Assessment of Fetal Well-being

Lead Sponsor:

Mayo Clinic

Conditions:

Fetal Testing

Transplacental Transfer of Acetaminophen

Eligibility:

FEMALE

18-44 years

Phase:

PHASE1

Brief Summary

This study has two aims: 1. to evaluate placental transfer of acetaminophen from mother to baby transplacentally given from 30 minutes to 24 hours prior to cesarean delivery (34 patients) 2. to under...

Eligibility Criteria

Inclusion

  • Inclusion Criteria
  • Pregnant females
  • Age 18-44
  • Any race
  • Any parity
  • Singleton Gestations
  • Weight between 60-90 kg
  • Exclusion Criteria
  • Acetaminophen Allergy
  • Contraindication to Acetaminophen Use
  • Chorioamnionitis
  • Preeclampsia
  • Diabetes Mellitus
  • Placental Abruption
  • Placenta Previa
  • Fetal Anomaly
  • Intrauterine growth restriction (IUGR)
  • Multiple Gestations
  • Maternal Medical Disease
  • Acetaminophen use in the last 3 days
  • Plan to donate or bank fetal cord blood

Exclusion

    Key Trial Info

    Start Date :

    September 1 2010

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    December 1 2011

    Estimated Enrollment :

    56 Patients enrolled

    Trial Details

    Trial ID

    NCT01211912

    Start Date

    September 1 2010

    End Date

    December 1 2011

    Last Update

    September 1 2014

    Active Locations (1)

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    Mayo Clinic in Rochester

    Rochester, Minnesota, United States, 55905