Status:
UNKNOWN
Hemofiltration in Burns: RESCUE (Randomized Controlled Evaluation of Hemofiltration in Adult Burn Patients With Septic Shock and Acute Renal Failure)
Lead Sponsor:
American Burn Association
Collaborating Sponsors:
United States Army Institute of Surgical Research
Tampa General Hospital
Conditions:
Burns
Hemofiltration
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The purpose of this study is determine if High-Volume Hemofiltration in addition to 'contemporary' care will result in an improvement of select clinical outcomes when compared to 'contemporary' care a...
Detailed Description
Acute renal failure (ARF) is a common and devastating complication in critically ill burn patients with mortality reported to be between 80 and 100%.(3-7) Despite recent advances in burn care, the una...
Eligibility Criteria
Inclusion
- All adult patients admitted to the burn intensive care unit (ICU) with burns of any size
- Acute renal failure as previously defined by the Veterans Affairs/ National Institutes of Health (VA/NIH) Acute Renal Failure Trial Network study investigators(2)
- Patient is \> 48 hours post-burn and in Septic Shock
- Patients 18 or older
- Patient/legally authorized representative willing to provide consent
Exclusion
- Age \<18
- Non-thermal injury (exfoliating skin disorders or necrotizing fasciitis)
- Pre-admission diagnosis of end stage renal failure
- Patients already on renal replacement therapy for more than 24 hours
- Patient not expected to survive more than 24 hours after randomization.
- Pregnancy
- Prisoners
Key Trial Info
Start Date :
August 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2018
Estimated Enrollment :
37 Patients enrolled
Trial Details
Trial ID
NCT01213914
Start Date
August 1 2011
End Date
September 1 2018
Last Update
April 6 2018
Active Locations (9)
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1
Arizona Burn Center
Phoenix, Arizona, United States, 85008
2
The Burn Center at Washington Hospital Center
Washington D.C., District of Columbia, United States, 20010
3
Tampa General Hospital
Tampa, Florida, United States, 33606
4
Doctors Hospital-Joseph M Still Burn Center
Augusta, Georgia, United States, 30909